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Clinicians and Pathologists
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Inclusion Body Hepatitis is a Primary Disease in Broilers in Canada Susantha Gomis1, Robert Goodhope1, Davor Ojkic2, Neil Ambrose3, Philip Willson4. 1Dept. of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada S7N 5B4. 2Animal Health Laboratory, University of Guelph, Box 3612, Guelph ON, Canada N1H 6R8. 3 26862 Furguson Avenue, Maple Ridge, British Colombia, Canada, V2W 1R9. 4 Vaccine and Infectious Disease Organization, 120 Veterinary Road, Saskatoon, SK, Canada S7N 5E3. ABSTRACT In recent years, Inclusion Body Hepatitis (IBH) emerged as an economically important disease in Canada. Recently, it has been reported that virulent IBH viruses are able to cause IBH as a primary disease in broilers without any immunosuppressive agents. The objective of this study was to identify the association of IBH with major immunosuppressive diseases of broilers like IBD and CIA. Serum samples from twenty-five broiler breeder flocks, and their progeny at hatch and at the time of slaughter were collected for IBDV and CIAV serology in Saskatchewan and Alberta, Canada. Necropsy of daily mortalities was conducted three times during the broiler grow-out phase. Immunity against IBD and CIA, measured by antibody titers, appeared to be at satisfactory levels in all broiler flocks that were affected by IBH. Hexon gene loop 1 analysis of IBH associated viruses isolated from the affected birds showed high identity to FAdV-11 (100.0%), FAdV-8a (99.4-100.0%) and FAdV-2 (99.4%). A group of viruses matched 93.7% FAdV7 strain x11a. The data support the observation that IBH in broilers in Western provinces of Canada is a primary disease with no known association with immunosuppression |
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